With Isaiah 53:4-6, we find ourselves in the centerpiece of the doctrine of salvation. This is the whole heart of Christianity. It assumes several things: the hopelessness of sinners to bear their own sins; the justice of a righteous God, who must appease His wrath; In that justice and mercy of God, the penalty is paid, but it is paid by a substitute. Thanks be to God for His unspeakable gift. It shows us the sinfulness of our sin and the greatness of the suffering that Christ endured for repentant sinners. God vindicated His just wrath for rebellion against His law. He vindicates His justice against them through the suffering (v4-6).